Docs of 2020- Latest Research Encompassing Physiology’s Updates
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Short-term sleep deprivation affects heart function
A study done on the cardiac effects of short-term sleep deprivation, specifically in the context of 24-hour shifts, has found that sleep deprivation can lead to a significant increase in cardiac contractility, blood pressure, and heart rate
The st...More
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Ovarian teratoma associated with anti-N-methyl D-aspartate receptor encephalitis: a report of 5 cases documenting prominent intratumoral lymphoid infiltrates.
Ovarian teratoma associated with anti-N-methyl D-aspartate receptor encephalitis: a report of 5 cases documenting prominent intratumoral lymphoid infiltrates
Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a condition wherein the immune...More
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New Therapies for Asthma and COPD
Obstructive lung disease is a subset of disorders such as COPD and asthma that decrease pulmonary function in adults and children alike. The etiologies for each of these diseases is different; however, on a molecular level, the inflammatory immune r...More
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A microfluidic chip to assess treatments for neuromuscular junction disorders
Michael Lin, Victoria Lu, Jessica Luo, Janell Mathus, Kyle Osborn
There are numerous diseases that have debilitating effects on muscle function as a result of the destruction to various parts of the neural muscular junction. Consequently, there...More
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OCS (Organ Care System): Preventing Reperfusion Injury in Heart Transplant Recipients
Kylie Mena
Derek Minor
Emily McLaughlin
Elle Meisner
As we learned in class, there are multiple issues that accompany ischemic tissue. Aside from needing to return oxygen to the tissue, there is the issue of reperfusion injury. When reperfusion...More
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GMO Lactobacillus for the Treatment of Hypertension
Zach Negley, Gen Nieves, Andrew Murphy, Tejasvi Niranjan
Yang, et. al. demonstrated the utility of genetically modified Lactobacillus to decrease hypertension in a rat model of spontaneous hypertension. The bacteria express an 8 kDa ACE inhibitory...More
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Diaphragm Muscle Adaptation to Sustained Hypoxia: Lessons from Animal Models with Relevance to High Altitude and Chronic Respiratory Diseases
The primary muscle used for inspiration is the diaphragm. Emerging data on recent animal model studies have shown that hypoxia contributes to diaphragm adaptation in chronic respiratory disease and high altitude. Interestingly, the diaphragm develop...More
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Altitude Training for Swimmers
Victoria Kuritza
Gabrielle Kuhn
Landon Kunzelman
Jonathan Knisley
Athletes in different sports are interested in the benefits of altitude training. The idea is that training in altitude increases red blood cell numbers which results in increased...More