The Role of Multimorbidity in Dementia among Elderly People Aged 60 Years and Above in Community

Abstract

Many studies have shown multimorbidities might be one of the key risk factors for accelerating cognitive decline in the elderly. The evidence of the impact of multimorbidity on dementia among elderly people in China is scarce in detail. This study was performed to examine the association between the prevalence of dementia and multimorbidity, as well as pattern of multimorbidity among the elderly in Shanghai. This was a cross-sectional study, with 5040 elderly individuals from 21 communities enrolled. The prevalence of dementia was assessed using the Mini-Mental State Examination (MMSE). The diagnosed chronic diseases including hypertension, diabetes, hyperlipidemia and coronary heart disease (CHD) were investigated such that multimorbidity was defined as individuals suffering from two or more chronic diseases at the same time. Data of 4945 older adults were analyzed. The overall prevalence of dementia and multimorbidity were 15.73% and 35.98%. Multivariate analysis showed multimorbidity was significantly negatively associated with dementia, and the risk of dementia in elderly individuals with 2, 3 or more chronic diseases was 1.283 and 2.034 times greater, respectively, than those who with no multimorbidity. Notably, elderly individuals with both diabetes and hyperlipidemia had the highest risk of dementia. In conclusion, Multimorbidity played a negative role in dementia among elderly people, dementia risk increases with the number of comorbidities, and the combination of diabetes and hyperlipidemia accentuates dementia risk at a greater level.

Presenters

Tingting Zhu
Assistant Researcher, Research Management Affairs Department, Shanghai Health Development Research Center, Shanghai, China

Yuhong Niu
Department Director, Shanghai Health Development Research Center, Shanghai, China

Details

Presentation Type

Poster Session

Theme

Medical Perspectives on Aging, Health, Wellness

KEYWORDS

ELDERLY, DEMENTIA, MULTIMORBIDITY, DIABETES, HYPERLIPIDEMIA